| Chemical Properties | Back Directory | [Boiling point ]
587.5±60.0 °C(predicted) | [density ]
1.385±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [pka]
2.12±0.10(predicted) |
| Hazard Information | Back Directory | [Uses]
PAR4 antagonist 5 (compound 1) is a PAR4 antagonist with an IC50 less than 20 μM and potent anti-platelet aggregation activity. PAR4 antagonist 5 can be used for research of thrombosis disease [1]. | [IC 50]
PAR4 | [References]
[1] Zhu X, et al. Preparation of cinnoline derivatives as PAR4 antagonists for prevention and/or treatment of thromboembolic disorders, China, CN117285527 A, 2023-12-26 |
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