ChemicalBook--->CAS DataBase List--->31059-54-8

31059-54-8

31059-54-8 Structure

31059-54-8 Structure
IdentificationBack Directory
[Name]

2-naphthoylethyltrimethylammonium
[CAS]

31059-54-8
[Synonyms]

Α-NETA
β-NETA
2-naphthoylethyltrimethylammonium
2-(beta-Naphthoyl)ethyltrimethylammonium iodide
2-Dimethylaminoethyl 2-naphthyl ketone methiodide
trimethyl-(3-naphthalen-2-yl-3-oxopropyl)azanium:iodide
[Molecular Formula]

C16H20NO.I
[MOL File]

31059-54-8.mol
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C, protect from light, stored under nitrogen
[solubility ]

DMSO: 3mg/ml; Methanol: Soluble
[form ]

A solid
[color ]

White to off-white
Hazard InformationBack Directory
[Description]

Choline acetyltransferase (ChAT) mediates the synthesis of the neurotransmitter acetylcholine from acetyl-CoA and choline. In addition to its critical role in neurosignaling, deficiencies in ChAT are linked to congenital myasthenic syndromes, Alzheimer’s disease, and multiple sclerosis. α-NETA is a stable, non-competitive, and slowly reversible inhibitor of ChAT (IC50 = 9 μM). This naturally fluorescent compound is a poor inhibitor of cholinesterases and carnitine acetyltransferase. α-NETA is commonly used in cells in culture.
[Uses]

Choline acetyltransferase (ChAT) mediates the synthesis of the neurotransmitter acetylcholine from acetyl-CoA and choline. In addition to its critical role in neurosignaling, deficiencies in ChAT are linked to congenital myasthenic syndromes, Alzheimer’s disease, and multiple sclerosis. α-NETA is a stable, non-competitive, and slowly reversible inhibitor of ChAT (IC50 = 9 μM). This naturally fluorescent compound is a poor inhibitor of cholinesterases and carnitine acetyltransferase. α-NETA is commonly used in cells in culture.[Cayman Chemical]
[storage]

Store at -20°C, protect from light, stored under nitrogen
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