ChemicalBook--->CAS DataBase List--->312930-75-9

312930-75-9

312930-75-9 Structure

312930-75-9 Structure
IdentificationBack Directory
[Name]

MMP3 inhibitor 1
[CAS]

312930-75-9
[Synonyms]

MMP3 inhibitor 1
Propanamide, N-hydroxy-2-[[4-[4-[6-(2-hydroxyethoxy)-2-pyridinyl]-3-methylphenyl]-1-piperidinyl]sulfonyl]-2-methyl-
[Molecular Formula]

C23H31N3O6S
[MDL Number]

MFCD31814417
[MOL File]

312930-75-9.mol
[Molecular Weight]

477.57
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[color ]

White to off-white
Hazard InformationBack Directory
[Biological Activity]

MMP3 inhibitor 1 is a potent and highly selective MMP-3 inhibitor with IC50 of 1 nM.
[in vitro]

MMP3 inhibitor 1 (Compound 27) inhibits MMP-1, MMP-2, MMP-9, and MMP-14 with IC 50 s of 14000, 529, 2420, and 20100 nM, respectively.

[target]

MMP-3

< span> 1 nM (IC 50 )

MMP-2

529 nM (IC 50 )

MMP-9

2420 nM (IC 50 )

MMP-1

< p> 14000 nM (IC 50 )

MMP-14

20100 nM (IC 50 )

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