| Identification | Back Directory | [Name]
ORTHO-NORNUCIFERINE | [CAS]
3153-55-7 | [Synonyms]
ORTHO-NORNUCIFERINE
O-demethyl nuciferine
(6aR)-5,6,6a,7-Tetrahydro-1-methoxy-6-methyl-4H-dibenzo[de,g]quinolin-2-ol
4H-Dibenzo[de,g]quinolin-2-ol, 5,6,6a,7-tetrahydro-1-methoxy-6-methyl-, (6aR)- | [Molecular Formula]
C18H19NO2 | [MDL Number]
MFCD01664604 | [MOL File]
3153-55-7.mol | [Molecular Weight]
281.35 |
| Chemical Properties | Back Directory | [Melting point ]
195-197℃ (ethyl acetate ) | [Boiling point ]
451.4±45.0 °C(Predicted) | [density ]
1.216±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
10.12±0.20(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
O-Nornuciferine, an aporphine-type alkaloid from lotus leaf, is a potent hERG channel inhibitor[1]. | [IC 50]
Human Endogenous Metabolite | [References]
[1] Ulrike Grienke, et al. Human Ether-à-go-go Related Gene (hERG) Channel Blocking Aporphine Alkaloids From Lotus Leaves and Their Quantitative Analysis in Dietary Weight Loss Supplements. J Agric Food Chem. 2015 Jun 17;63(23):5634-9. PMID:260352 |
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