ChemicalBook--->CAS DataBase List--->32274-52-5

32274-52-5

32274-52-5 Structure

32274-52-5 Structure
IdentificationBack Directory
[Name]

3-[4-Acetyl-2,3,6-trihydroxy-5-(3-methyl-2-butenyl)benzyl]-6-ethyl-4-hydroxy-5-methyl-2H-pyran-2-one
[CAS]

32274-52-5
[Synonyms]

Arzanol
Homoarenol
Arzanol from Helichrysum italicum, >=98%
3-[4-Acetyl-2,3,6-trihydroxy-5-(3-methyl-2-butenyl)benzyl]-6-ethyl-4-hydroxy-5-methyl-2H-pyran-2-one
3-[[3-Acetyl-2,4,6-trihydroxy-5-(3-methyl-2-buten-1-yl)phenyl]methyl]-6-ethyl-4-hydroxy-5-methyl-2H-pyran-2-one
2H-Pyran-2-one, 3-[[3-acetyl-2,4,6-trihydroxy-5-(3-methyl-2-buten-1-yl)phenyl]methyl]-6-ethyl-4-hydroxy-5-methyl-
[Molecular Formula]

C22H26O7
[MDL Number]

MFCD28168041
[MOL File]

32274-52-5.mol
[Molecular Weight]

402.44
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[form ]

powder
[biological source]

Helichrysum italicum
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

Arzanol has been used to test its effects as an autophagy modulator on HeLa cells and bladder cancer cells
[Biological Activity]

Arzanol is a polyphenol compound extracted from the plant Helichrysum italicum which grows in the Mediterranean area. Arzanol is known for its anti-inflammatory and antimicrobial activities. The anti-inflammatory activity was verified in an in-vivo r at model and was found to suppress the inflammatory response of the carrageenan-induced pleurisy. Moreover it was found to have an anti-HIV-1 activity. Arzanol inhibits COX-2-derived prostaglandin synthase-1 (mPGES-1) Inhibitor in-vitroin human stimulated monocytes.
Arzanol inhibits the activation of inflammatory transcription factor NFKBHIV replication in T cellsreleases of IL-1βIL-6IL-8and TNF-α,and biosynthesis of PGE2 by potentially inhibiting the mPGES-1 enzyme.''Arzanol is known for its anti-inflammatory and antimicrobial activities. The anti-inflammatory activity was verified in an in-vivo r
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