ChemicalBook--->CAS DataBase List--->324759-76-4

324759-76-4

324759-76-4 Structure

324759-76-4 Structure
IdentificationBack Directory
[Name]

CCT020312
[CAS]

324759-76-4
[Synonyms]

CCT020312
2(1H)-Quinolinone, 6-bromo-3-[5-(4-bromophenyl)-1-[3-(diethylamino)-1-oxopropyl]-4,5-dihydro-1H-pyrazol-3-yl]-4-phenyl-
[Molecular Formula]

C31H30Br2N4O2
[MOL File]

324759-76-4.mol
[Molecular Weight]

650.4
Chemical PropertiesBack Directory
[density ]

1.48±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: soluble
[form ]

A solid
[pka]

9.43±0.70(Predicted)
[color ]

Light yellow to yellow
Spectrum DetailBack Directory
[Spectrum Detail]

CCT020312(324759-76-4)1HNMR
Hazard InformationBack Directory
[Biological Activity]

CCT020312 is a selective activator of EIF2AK3/PERK. It induces phosphorylation of EIF2A in cells.
[in vitro]

CCT020312 treatment effectively inhibits cell proliferation (as measured at 96 hours) even if treatment is for 2 hours only with subsequent compound washout, indicating that CCT020312 is capable of eliciting durable rather than transient cytostasis.
[target]

EIF2AK3/PERK.

[storage]

Store at -20°C
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