| Identification | Back Directory | [Name]
alpha-[(2-pyridylamino)methyl]benzyl alcohol monohydrochloride | [CAS]
326-43-2 | [Synonyms]
Vazalmin
Firmalgil
Phenyramidol HCl
FENYRAMIDOLHYDROCHLORIDE
alpha-[(2-pyridylamino)methyl]benzyl alcohol monohydrochloride | [EINECS(EC#)]
206-308-3 | [Molecular Formula]
C13H15ClN2O | [MDL Number]
MFCD00242757 | [MOL File]
326-43-2.mol | [Molecular Weight]
250.724 |
| Hazard Information | Back Directory | [Originator]
Analexin, Mallinckrodt Inc., US ,1960 | [Uses]
Analgesic; relaxant
(skeletal muscle). | [Manufacturing Process]
A mixture containing 188 g (0.20 mol) of 2-arninopyridine, 0.55 g of lithium amide and 75 cc of anhydrous toluene was refluxed for 1.5 hours. Styrene oxide (12.0 g = 0.10 mol) was then added to the reaction mixture with stirring over a period of ten minutes. The reaction mixture was stirred and refluxed for an additional 3.5 hours. A crystalline precipitate was formed during the reaction which was removed by filtration, MP 170°C to 171°C. 1.5 g. The filtrate was concentrated to dryness and a dark residue remained which was crystallized from anhydrous ether; yield 6.0 g. Upon recrystallization of the crude solid from 30 cc of isopropyl alcohol, 2.0 g of a light yellow solid was isolated; MP 170° to 171°C. | [Therapeutic Function]
Analgesic, Muscle relaxant |
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