| Identification | Back Directory | [Name]
Shz-1 | [CAS]
326886-05-9 | [Synonyms]
Shz-1
(E)-N-(5-bromo-2-hydroxybenzylidene)benzenesulfonohydrazide
Benzenesulfonic acid [(5-bromo-2-hydroxyphenyl)methylene]hydrazide
2-[(5-BroMo-2-hydroxyphenyl)Methylene]hydrazide Benzenesulfonic Acid | [Molecular Formula]
C13H11BrN2O3S | [MDL Number]
MFCD00853265 | [MOL File]
326886-05-9.mol | [Molecular Weight]
355.21 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [solubility ]
DMSO: soluble10mg/mL, clear | [form ]
powder | [color ]
white to beige | [Stability:]
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month. |
| Hazard Information | Back Directory | [Description]
SHZ-1 (326886-05-9) triggers cardiac mRNA and protein expression in a variety of embryonic and adult stem/progenitor cells including human mobilized peripheral blood mononuclear cells (M-PBMC).1?A lead compound for the discovery of drugs which promote myocardial repair/regeneration by activating cardiac differentiation in M-PBMC. Cell permeable. | [Uses]
2-[(5-Bromo-2-hydroxyphenyl)methylene]hydrazide Benzenesulfonic Acid, is a sulfonylhydrazone that activates cardiac differentiation, inducing the expression of early cardiac genes in mouse pluripotent and embryonic stem cells in vitro at low micromolar concentrations. | [storage]
Store at -20°C | [References]
1) Sadek?et al. (2008),?Cardiogenic small molecules that enhanced myocardial repair by stem cells; Proc. Natl. Acad. Sci. USA,?105?6063 |
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| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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