| Identification | Back Directory | [Name]
PDK1/Akt/Flt Dual Pathway Inhibitor | [CAS]
331253-86-2 | [Synonyms]
KP-23172
KP 23172,KP23172
PDK1/Akt inhibitor
DPANHMGWPXVBQI-UHFFFAOYSA-N
PDK1/Akt/Flt Dual Pathway Inhibitor
KP372-1(PDK1/Akt/Flt Dual Inhibitor) | [Molecular Formula]
C10H4N6O | [MOL File]
331253-86-2.mol | [Molecular Weight]
224.18 |
| Chemical Properties | Back Directory | [density ]
2.01±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: 10mg/mL | [form ]
solid | [pka]
-3.05±0.20(Predicted) | [color ]
yellow |
| Hazard Information | Back Directory | [Uses]
PDK1/Akt/Flt Dual Pathway Inhibitor is a cell-permeable compound that selectively induces apoptosis. | [Biological Activity]
Cell permeable: yes''Primary Target
Both PDK1 and Akt activities''Product does not compete with ATP.''Reversible: no''Target IC50: 1.051.91and 0.43 μM for AML with wild-type Flt3single mutant ITD/D835and double mutant Flt3-ITD-TDKrespectively |
|
| Company Name: |
SPIRO PHARMA
|
| Tel: |
|
| Website: |
www.spiropharma.com.cn |
|