| Identification | Back Directory | [Name]
Benzenepropanamide, N-[(8-hydroxy-7-quinolinyl)(4-methoxyphenyl)methyl]- | [CAS]
333314-79-7 | [Synonyms]
HIF1-IN-3
N-((8-hydroxyquinolin-7-yl)(4-methoxyphenyl)methyl)-3-phenylpropanamide
Benzenepropanamide, N-[(8-hydroxy-7-quinolinyl)(4-methoxyphenyl)methyl]- | [Molecular Formula]
C26H24N2O3 | [MOL File]
333314-79-7.mol | [Molecular Weight]
412.48 |
| Chemical Properties | Back Directory | [Boiling point ]
698.1±55.0 °C(Predicted) | [density ]
1.229±0.06 g/cm3(Predicted) | [storage temp. ]
4°C, protect from light | [solubility ]
DMSO : 125 mg/mL (303.04 mM; Need ultrasonic) | [form ]
Solid | [pka]
4.31±0.50(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Biological Activity]
HIF1-IN-3 (compound F4) is a potent HIF1 inhibitor with an EC50 value of 0.9 μM. HIF1-IN-3 can be used for researching anticancer[1]. | [storage]
4°C, protect from light | [References]
[1]. Poloznikov AA, et al. Structure-activity relationship for branched oxyquinoline HIF activators: Effect of modifications to phenylacetamide "tail". Biochimie. 2017;133:74-79. |
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