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343263-95-6

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343263-95-6 Structure

343263-95-6 Structure
IdentificationBack Directory
[Name]

DH 97
[CAS]

343263-95-6
[Synonyms]

DH 97
N-PENTANOYL-2-BENZYLTRYPTAMINE
N-[2-(2-benzyl-1H-indol-3-yl)ethyl]pentanamide
1-Pentanone,1-[3-(2-aminoethyl)-2-(phenylmethyl)-1H-indol-1-yl]-
[Molecular Formula]

C22H26N2O
[MDL Number]

MFCD02262121
[MOL File]

343263-95-6.mol
[Molecular Weight]

334.45
Chemical PropertiesBack Directory
[storage temp. ]

Store at RT
[solubility ]

DMSO: soluble
[form ]

A crystalline solid
Hazard InformationBack Directory
[Description]

DH 97 is an antagonist of melatonin receptor 2 (MT2; Kis = 252 and 1,100 for human MT2 and MT1 receptors, respectively).
[Definition]

ChEBI: N-[2-[2-(phenylmethyl)-1H-indol-3-yl]ethyl]pentanamide is a member of indoles.
[Biological Activity]

A relatively potent MT 2 melatonin receptor antagonist (pK i value = 8.03), displaying 89- and 229-fold selectivity over MT 1 and GPR50 (melatonin-related orphan receptor) respectively.
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