| Identification | Back Directory | [Name]
3 3' 5-TRIIODO-L-THYRONINE SODIUM SALT& | [CAS]
345957-19-9 | [Synonyms]
Liothyronine sodium hydrate
3,3μ,5-Triiodo-L-thyronine hydrate sodium salt
3,3',5-Triiodo-L-thyronine sodium salt hydrate 95%
3 3' 5-TRIIODO-L-THYRONINE SODIUM SALT& USP/EP/BP
Sodium(2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoatehydrate(1:1:1) | [Molecular Formula]
C15H11I3NO4Na | [MDL Number]
MFCD12546154 | [MOL File]
345957-19-9.mol | [Molecular Weight]
672.96 |
| Chemical Properties | Back Directory | [Melting point ]
205 °C (dec.)(lit.) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 0.25 mg/ml,DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml,DMSO: 1 mg/ml | [form ]
A crystalline solid | [optical activity]
[α]22/D +21.5°, c = 2 in 1 N HCl: ethanol, 1:2 |
| Hazard Information | Back Directory | [Description]
3,3'',5-Triiodo-L-thyronine (T3) is a thyroid hormone. It is produced by 5''-monodeiodination of the prohormone thyroxine (T4) in various tissues, including liver and kidney. T3 is an agonist of thyroid hormone receptors TRα and TRβ (Kis = 2.3 nM for both) that modulates diverse biological properties, including metabolism, cardiac function, growth, and redox signaling. It also functions as an inhibitor of L-type amino acid transporter 1 (LAT1), inhibiting LAT1-mediated leucine uptake in HEK293 cells when used at a concentration of 10 μM. | [storage]
Store at -20°C |
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