| Identification | Back Directory | [Name]
N-desferriferrichrome | [CAS]
34787-28-5 | [Synonyms]
deferrichrome
DesferrichroMe
Deferriferrichrome
Ferrichrome Iron-free
N-desferriferrichrome
Cyclo(glycylglycylglycyl-N5-acetyl-N5-hydroxy-L-ornithyl-N5-acetyl-N5-hydroxy-L-ornithyl-N5-acetyl-N5-hydroxy-L-ornithyl) | [Molecular Formula]
C27H45N9O12 | [MDL Number]
MFCD28899080 | [MOL File]
34787-28-5.mol | [Molecular Weight]
687.7 |
| Hazard Information | Back Directory | [Description]
Ferrichrome is a hydroxamate siderophore produced by various fungi, including U. sphaerogena, that facilitates iron chelation and uptake by these organisms. It can be utilized as a heterologous siderophore by bacteria, including P. aeruginosa and V. parahaemolyticus. Ferrichrome (0.8 μM) inhibits proliferation of murine spleen mononuclear cells induced by concanavalin A and reduces the number of concanavalin A-stimulated CD4+ T cells expressing the IL-2 receptor. It also inhibits heme-catalyzed oxidation of LDL by hydrogen peroxide in a concentration-dependent manner. | [Uses]
Growth-promoting iron chelator. Ferrichrome iron-free from Ustilago sphaerogena. | [Definition]
ChEBI: A homodetic cyclic peptide composed from two units of three glycyl and three N5-acetyl-N5-hydroxy-L-ornithyl residues. | [Biochem/physiol Actions]
Growth-promoting iron chelator |
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