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351533-80-7

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351533-80-7 Structure

351533-80-7 Structure
IdentificationBack Directory
[Name]

14(15)-EpEDE
[CAS]

351533-80-7
[Synonyms]

14(15)-EpEDE
ZXBWLXDDSYHRTE-QGIBGKBZSA-N
14,15-Epoxy-Eicosadienoic Acid
13-(3-pentyl-2-oxiranyl)-8(Z),11(Z)-tridecadienoic acid
[Molecular Formula]

C20H34O3
[MOL File]

351533-80-7.mol
[Molecular Weight]

322.48
Chemical PropertiesBack Directory
[solubility ]

DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml; Ethanol: 20 mg/ml
Safety DataBack Directory
[Symbol(GHS) ]


GHS02,GHS08
[Signal word ]

Danger
[Hazard statements ]

H225-H350
[Precautionary statements ]

P201-P202-P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P308+P313-P370+P378-P403+P235-P405-P501
Hazard InformationBack Directory
[Description]

8,11,14-Eicosatrienoic acid, also known as dihomo-γ-linolenic acid , is a polyunsaturated fatty acid (PUFA) produced from γ-linolenic acid by the action of fatty acid elongases. It can be metabolized by the cyclooxygenase pathway to produce 1-series prostaglandins (PGs) (e.g., PGE1). (±)14(15)-EpEDE is an EpEDE acid formed from 8,11,14-eicosatrienoic acid. This monoepoxide can be generated from the PUFA, in vitro, by the action of a strong oxidizing agent. Alternatively, this compound may be produced, in vivo, by epoxidation of the PUFA by cytochrome P450 epoxygenases. The biological properties of this compound are poorly understood.
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