Identification | Back Directory | [Name]
3-(o-chlorophenyl)-3-hydroxy-3-phenylpropiononitrile | [CAS]
35173-29-6 | [Synonyms]
1-(o-Chlorophenyl)-2-cyano-1-phenyl-ethenol 2-Chloro-hydroxy-phenyl benzene-propanenitrile 3-(2-chlorophenyl)-3-hydroxy-3-phenylpropanenitrile 3-(O-CHLOROPHENYL)-3-HYDROXY-3-PHENYL PROPIONITRILE 3-(o-chlorophenyl)-3-hydroxy-3-phenylpropiononitrile | [EINECS(EC#)]
252-419-5 | [Molecular Formula]
C15H12ClNO | [MDL Number]
MFCD09834384 | [MOL File]
35173-29-6.mol | [Molecular Weight]
257.71 |
Hazard Information | Back Directory | [Chemical Properties]
Crystalline compounds. Melting point 88-91 ℃. | [Uses]
3-(o-chlorophenyl)-3-hydroxy-3-phenylpropiononitrile is the intermediate of the enemy cough. | [Synthesis]
Use o-chlorobenzoic acid to chlorinate with thionyl chloride to generate o-chlorobenzoyl chloride, which is then condensed with benzene under the participation of aluminum trichloride to obtain o-chlorobenzoyl. 3-(O-chlorophenyl)-3-hydroxy-3-phenylpropiononitrile is obtained by condensing the latter with acetonitrile under the action of sodium amide. |
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