| Identification | Back Directory | [Name]
TQS | [CAS]
353483-92-8 | [Synonyms]
TQS
4-Naphthalen-1-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide
3a,4,5,9b-Tetrahydro-4-(1-naphthalenyl)-3H-cyclopentan[c]quinoline-8-sulfonamide
Inhibitor,modulator,acetylcholine,Nicotinic acetylcholine receptors,nAChR,allosteric,neuroinflammatory,positive,pain,inhibit,TQS,nicotinic | [Molecular Formula]
C22H20N2O2S | [MOL File]
353483-92-8.mol | [Molecular Weight]
376.47 |
| Chemical Properties | Back Directory | [Boiling point ]
609.8±65.0 °C(Predicted) | [density ]
1.311±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble to 50 mM in DMSO | [form ]
Powder | [pka]
10.21±0.40(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
TQS is a positive allosteric modulator (Type II) of alpha7 nACh receptors, functional human α7 nicotinic acetylcholine receptor (nAChR) generated from Escherichia coli that opens a new avenue for producing mammalian Cys-loop receptors to facilitate structure-based rational drug design. |
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| Company Name: |
BOC Sciences
|
| Tel: |
|
| Website: |
https://www.bocsci.com |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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