| Identification | Back Directory | [Name]
DINOPROST ETHANOLAMIDE | [CAS]
353787-70-9 | [Synonyms]
PGF2ALPHA-EA
DINOPROST ETHANOLAMIDE
PROSTAGLANDIN F2A ETHANOLAMIDE
Prostaglandin F2α Ethanolamide
ProstaglandinF2α ethanolamide
PROSTAGLANDIN F2ALPHA ETHANOLAMIDE
Prostaglandin F2 Ethanolamide MaxSpecStandard
Prostaglandin F2α Ethanolamide MaxSpec? Standard
Prostaglandin F2α Ethanolamide Lipid Maps MS Standard
N-(2-Hydroxyethyl)-9α,11α,15S-trihydroxy-prosta-5Z,13E-dien-1-amide
N-(2-HYDROXYETHYL)-9A,11A,15S-TRIHYDROXY-PROSTA-5Z,13E-DIEN-1-AMIDE
N-(2-HYDROXYETHYL)-9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-AMIDE
Dinoprost ethanolamide, N-(2-Hydroxyethyl)-9α,11α,15S-trihydroxy-prosta-5Z,13E-dien-1-amide
(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]-N-(2-hydroxyethyl)hept-5-enamide | [Molecular Formula]
C22H39NO5 | [MDL Number]
MFCD03411991 | [MOL File]
353787-70-9.mol | [Molecular Weight]
397.55 |
| Hazard Information | Back Directory | [Description]
Prostaglandin F2α ethanolamide (PGF2α-EA) is produced by COX-2 metabolism of the endogenous cannabinoid, arachidonoyl ethanolamide (AEA), found in brain, liver, and other mammalian tissues. AEA can be metabolized directly by the sequential action of COX-2 and specific PG synthases to produce ethanolamide congeners of the classical PGs. PGF2α-EA has also been reported to be biosynthesized by this mechanism when AEA was infused into the lung and liver of living mice. PGF2α-EA is a potent dilator (EC50 = 58 nM) of the cat iris sphincter, which is a model system for testing potential intraocular hypotensive agents. | [Definition]
ChEBI: Prostaglandin F2alpha 1-ethanolamide is an N-acylethanolamine compound formed by a condensation of prostaglandin F2alpha and ethanolamine. It is a N-acylethanolamine and a prostaglandins Falpha. It is functionally related to a prostaglandin F2alpha. | [Biological Activity]
The end-product of the reaction of arachidonyl ethanolamide (AEA), an endogenous ligand for brain cannabinoid receptor, with COX-2. |
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