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3563-58-4

3563-58-4 Structure

3563-58-4 Structure
IdentificationBack Directory
[Name]

chloralodol
[CAS]

3563-58-4
[Synonyms]

Lora
Mecoral
Medodorm
chloralodol
Chlorhexadol
2-Methyl-4-(2,2,2-trichloro-1-hydroxyethoxy)-2-pentanol
2-methyl-4-(2,2,2-trichloro-1-hydroxyethoxy)pentan-2-ol
2-methyl-4-(2,2,2-trichloro-1-hydroxy-ethoxy)pentan-2-ol
2-Pentanol, 2-methyl-4-(2,2,2-trichloro-1-hydroxyethoxy)-
[EINECS(EC#)]

222-634-9
[Molecular Formula]

C8H15Cl3O3
[MOL File]

3563-58-4.mol
[Molecular Weight]

265.56
Chemical PropertiesBack Directory
[Melting point ]

102-104°
[Boiling point ]

304.7±37.0 °C(Predicted)
[density ]

1.348±0.06 g/cm3(Predicted)
[pka]

10.73±0.20(Predicted)
Hazard InformationBack Directory
[Originator]

Chloralodol,Shanghai Lancheng Corporation
[Uses]

Mechloral is a hypnotic/sedative.
[Definition]

ChEBI: Chloralodol is a tertiary alcohol.
[Manufacturing Process]

472 g of 2-methyl-2,4-pentanediol (4 moles) are heated to 70°-80°C in a bowl, and 660 g of chloral hydrate (4 moles) are added under stirring until all of chloral hydrate is dissolved. The temperature, which decreases during the addition, then increased to 60° to 70°C. When reaction mixture has become a nearly dry crystal powder, the powder is subjected to further drying by slight heating. Yield of raw product is about 1060 g. Recrystallization is carried out from tetrachloromethane, and the yield is 980 g (about 92 %).
[Brand name]

Lora (Wallace).
[Therapeutic Function]

Hypnotic
Safety DataBack Directory
[DEA Controlled Substances]

CSCN: 2510
CSA SCH: Schedule III
NARC: No
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