| Identification | Back Directory | [Name]
OXYMORPHONE HCL NARCOTIC ANALGESIC | [CAS]
357-07-3 | [Synonyms]
OxyMorphone HCl
numorphanhydrochloride
oxymorphone hydrochloride
oxymorphinonehydrochloride
OXYMORPHONE HCL NARCOTIC ANALGESIC
3,14-dihydroxy-4,5-alpha-epoxy-17-methyl-morphinan-6-onhydrochloride
4,5-alpha-epoxy-3,14-dihydroxy-17-methylmorphinan-6-onehydrochloride
(5alpha)-4,5-epoxy-3,14-dihydroxy-17-methylmorphinan-6-one hydrochloride
morphinan-6-one,4,5-epoxy-3,14-dihydroxy-17-methyl-,hydrochloride,(5-alpha
Morphinan-6-one,4,5-epoxy-3,14-dihydroxy-17-Methyl-, hydrochloride (1:1), (5a)-
(4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-methyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one:hydrochloride
(4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-methyl-2,3,4,4a,5,6-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7(7aH)-one hydrochloride | [EINECS(EC#)]
206-610-5 | [Molecular Formula]
C17H21ClNO4 | [MOL File]
357-07-3.mol | [Molecular Weight]
338.806 |
| Chemical Properties | Back Directory | [solubility ]
DMF: 30 mg/ml; DMSO: 30 mg/ml; PBS (pH 7.2): 10 mg/ml | [form ]
A crystalline solid | [color ]
Yellowish-tan powder | [Stability:]
Hygroscopic |
| Safety Data | Back Directory | [RIDADR ]
3249 | [HazardClass ]
6.1(b) | [PackingGroup ]
III | [Toxicity]
LD50 orl-mus: 402 mg/kg THERAP15,1208,60 |
| Hazard Information | Back Directory | [Uses]
Analgesic (narcotic). | [Definition]
ChEBI: Oxymorphone hydrochloride is a member of phenanthrenes. | [Brand name]
Numorphan (Endo); Opana (Endo). | [Clinical Use]
Oxymorphone is a potent μ agonist (10 times greater than morphine) that is used to treat severe
pain. It is used by intramuscular, subcutaneous, intravenous, and rectal routes of administration.
The intramuscular dose of oxymorphone (1 mg) has a half-life of 3 to 4 hours. It is a Schedule II
drug. Oxymorphone, because of its 14-hydroxy group, has low antitussive activity. | [Safety Profile]
Poison by ingestion, intravenous, intraperitoneal, and subcutaneous routes. An experimental teratogen. When heated to decomposition it emits toxic fumes of NOx and HCl. |
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