| Identification | Back Directory | [Name]
METOMIDATEHYDROCHLORIDE | [CAS]
35944-74-2 | [Synonyms]
Nsc168403
1H-Imidazole-4-carboxylicacid,1-(10-bromophenyl)-
Methyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate hydrochloride
1H-Imidazole-5-carboxylic acid,1-(1-phenylethyl)-,methyl ester,hydrochloride(1:1)
1H-Imidazole-5-carboxylic acid, 1-(1-phenylethyl)-, methyl ester, monohydrochloride
Metomidate Hydrochloride (50 mg) (methyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate hydrochloride)
Metomidate Hydrochloride (methyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate hydrochloride) (1268772) | [Molecular Formula]
C13H14N2O2.ClH | [MOL File]
35944-74-2.mol | [Molecular Weight]
266.727 |
| Chemical Properties | Back Directory | [Melting point ]
173-174 °C | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
Acetone (Slightly), Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [color ]
White to Off-White | [InChI]
InChI=1S/C13H14N2O2.ClH/c1-10(11-6-4-3-5-7-11)15-9-14-8-12(15)13(16)17-2;/h3-10H,1-2H3;1H | [InChIKey]
NZEDTZKNEKPBGR-UHFFFAOYSA-N | [SMILES]
N1(C=NC=C1C(=O)OC)C(C)C1=CC=CC=C1.Cl |
| Hazard Information | Back Directory | [Uses]
Metomidate Hydrochloride is used as an anesthetic for veterinary use. | [Mechanism of action]
As mentioned earlier, metomidate has been suggested to block the stress response. Imidazole anesthetics (e.g., metomidate and etomidate) interrupt cortisol synthesis in mammals by suppressing the enzyme 11-beta-hydroxylase, which is necessary for cortisol production. |
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