| Identification | Back Directory | [Name]
Dexamethasone sodium phosphate EP Impurity B | [CAS]
360-63-4 | [Synonyms]
Unii-yjo1F9W10r
Einecs 206-636-7
Betamethasone phosphate
Betamethasone 21-phosphate
Betamethasone 21-phopsphate
Dexamethasone Impurity B(EP)
Betamethasone dihydrogen phosphate
Betamethasone 21-(dihydrogen phosphate)
Betamethasone-4,6,11,12,12-d5 21-Phosphate
9-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 21-phosphate
9-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 21-phosphoric acid
(11β,16β)-9-Fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4 -dien-21-yl dihydrogen phosphate
9-fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 21-(hydrogen phosphonate)
Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, (11beta,16beta)-
Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, (11β,16β)- (9CI)
Pregna-1,4-diene-3,20-dione, 9-fluoro-11-beta,17,21-trihydroxy-16-beta-methyl-, 21-(dihydrogen phosphate)
Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16β-methyl-, 21-(dihydrogen phosphate) (7CI, 8CI)
Betamethasone phosphateQ: What is
Betamethasone phosphate Q: What is the CAS Number of
Betamethasone phosphate
Betamethasone Phosphate-D4Q: What is
Betamethasone Phosphate-D4 Q: What is the CAS Number of
Betamethasone Phosphate-D4 | [EINECS(EC#)]
206-636-7 | [Molecular Formula]
C22H30FO8P | [MDL Number]
MFCD01698987 | [MOL File]
360-63-4.mol | [Molecular Weight]
472.44 |
| Hazard Information | Back Directory | [Originator]
Bentelan,Biofutura | [Uses]
Glucocorticoid. | [Definition]
ChEBI: Betamethasone phosphate is a steroid phosphate that is the 21-O-phospho derivative of betamethasone. It has a role as an anti-inflammatory agent and an immunosuppressive agent. It is a steroid phosphate, an 11beta-hydroxy steroid, a fluorinated steroid, a 17alpha-hydroxy steroid, a 20-oxo steroid, a 3-oxo-Delta(1),Delta(4)-steroid and a tertiary alpha-hydroxy ketone. It is functionally related to a betamethasone. It is a conjugate acid of a betamethasone phosphate(2-). | [Manufacturing Process]
A solution of bistriethylamine phosphate was prepared by slowly adding 2.36
ml of 85% phosphoric acid to 20 ml of acetonitrile containing 9.9 ml, of
triethylamine at 20°C. This solution was added to a stirred mixture of 4.70 g
of 9α-fluoro-11β,17α,21-trihydroxy-16α-methyl-1,4-pregnadiene-3,20-dione
21-methanesulfonate and 20 ml of acetonitrile. The mixture was heated under
reflux for 4 h and then evaporated under reduced pressure to a volume of 12
ml. This mixture was a concentrated solution of 9α-fluoro-11β,17α,21-
trihydroxy-16α-methyl-1,4-pregnadiene-3,20-dione 21-phosphate
triethylamine salt with some inorganic phosphate.
The salt of 9α-fluoro-11β,17α,21-trihydroxy-16α-methyl-1,4-pregnadiene-
3,20-dione 21-phosphate may be converted to 9α-fluoro-11β,17α,21-
trihydroxy-16α-methyl-1,4-pregnadiene-3,20-dione 21-phosphate by
treatment with acid (for example HCl). | [Brand name]
Celestone (Schering). | [Therapeutic Function]
Glucocorticoid |
|
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Ralington Pharma
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PI & PI BIOTECH INC.
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