| Identification | Back Directory | [Name]
N-(9-beta-D-Ribofuranosyl-9H-furin-6-yl)-butyramide cyclic 3',5'-(hydrogen phosphate) 2'-butyrate | [CAS]
362-74-3 | [Synonyms]
BUCLADESINE
N-(9-beta-D-Ribofura
Cyclic AMP dibutyrate
Dibutyryl 3',5'-Cyclic AMP
Dibutyryl cyclic 3',5'-AMP
3',5'-Cyclic AMP dibutyrate
-(hydrogen phosphate) 2'
CalciuM Dibutyacyladenosine
Bucladesine (Dibutyryl-cAMP)
Butyryladenosine Cyclophosphate
Calciuml Dibutyryladenosine Cyclophosphate
Dibutyryladenosine cyclic 3',5'-monophosphate
n-6,o-2'-dibutyryl adenosine cyclic 3':5'-monophosphate
N-(9-beta-D-Ribofuranosyl-9H-furin-6-yl)-butyramide cyclic 3'
n-(9-beta-d-ribofuranosyl-9h-furin-6-yl)-butyramide cyclic 3',5'-(hydrogen phosphate) 2'-butyrate
N-(9-beta-D-Ribofuranosyl-9H-furin-6-yl)-butyramide cyclic 3',5'-(hydrogen phosphate) 2'-butyrate USP/EP/BP | [EINECS(EC#)]
206-649-8 | [Molecular Formula]
C18H24N5O8P | [MDL Number]
MFCD00243003 | [MOL File]
362-74-3.mol | [Molecular Weight]
469.389 |
| Chemical Properties | Back Directory | [density ]
1.72±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer | [solubility ]
DMSO; Methano | [form ]
Solid | [pka]
0.82±0.60(Predicted) | [color ]
White |
| Hazard Information | Back Directory | [Description]
Bucladesine is a cyclic nucleotide derivative that mimics the action of endogenous CYCLIC AMP and is capable of permeating the cell membrane. It has vasodilator properties and is used as a cardiac stimulant. (From Merck Index, 11th ed) | [Uses]
Bucladesine is a cell permeable cAMP analog. The compound is used in a wide variety of research applications because it mimics cAMP and can induce normal physiological responses when added to cells in experimental conditions. cAMP is only able to elicit minimal responses in these situations. The neurite outgrowth instigated by bucladesine in cell cultures has been shown to be enhanced by nardosinone. | [Definition]
ChEBI: A 3',5'-cyclic purine nucleotide that is the 2'-butanoate ester and 6-N-butanoyl derivative of 3',5'-cyclic AMP. |
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