| Identification | Back Directory | [Name]
Glucagon Receptor Antagonist, Control | [CAS]
362482-00-6 | [Synonyms]
Glucagon Receptor Antagonist, Control
Glucagon Receptor Antagonist Inactive Control
4-bromo-N-[3-cyano-6-(2-methylbutan-2-yl)-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]benzamide | [Molecular Formula]
C21H23BrN2OS | [MDL Number]
MFCD01344061 | [MOL File]
362482-00-6.mol | [Molecular Weight]
431.39 |
| Hazard Information | Back Directory | [Description]
Glucagon receptor antagonist inactive control is an analog of glucagon receptor antagonist I .1 It inhibits glucagon binding to the glucagon receptor (GCGR) by only 20% in CHO cells expressing human GCGR when used at a concentration of 10 μM. Glucagon receptor antagonist inactive control has no effect on glucagon-induced glycogenolysis in primary human hepatocytes when used at concentrations of 10 or 30 μM. | [References]
1. Qureshi, S.A., Candelore, M.R., Xie, D., et al. A novel glucagon receptor antagonist inhibits glucagon-mediated biological effects Diabetes 53(12),3267-3273(2004). |
|
| Company Name: |
Specs
|
| Tel: |
+31 15 251 8111 |
| Website: |
www.specs.net |
|