36396-99-3

Directory

36396-99-3 Structure

Identification	Back Directory
[Name] N6-CYCLOHEXYLADENOSINE
[CAS] 36396-99-3
[Synonyms] CHA Cyclohexyladenosine N-Cyclohexyladenosine N6-CYCLOHEXYLADENOSINE Adenosine, N-cyclohexyl- N6-Cyclohexyladenosine,CHA N(sup 6)-cyclohexyladenosine (2R,4S)-4-fluoropyrrolidine-6-carboxylicacid N6-CYCLOHEXYLADENOSINE (CHA) SELECTIVE A 1 ADENOSIN (2R,3R,4S,5R)-2-(6-(CyclohexylaMino)-9H-purin-9-yl)-5-(hydroxyMethyl)tetrahydrofuran-3,4-diol
[Molecular Formula] C16H23N5O4
[MDL Number] MFCD00036808
[MOL File] 36396-99-3.mol
[Molecular Weight] 349.38

Chemical Properties	Back Directory
[Melting point ] 182 - 184°C
[Boiling point ] 675.2±65.0 °C(Predicted)
[density ] 1.71±0.1 g/cm3(Predicted)
[storage temp. ] 2-8°C
[solubility ] DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
[form ] Solid
[pka] 13.12±0.70(Predicted)
[color ] White to Off-White
[Stability:] Hygroscopic

Safety Data	Back Directory
[Symbol(GHS) ] GHS07
[Signal word ] Warning
[Hazard statements ] H302-H315-H319-H332-H335
[Precautionary statements ] P261-P280-P305+P351+P338
[WGK Germany ] 3
[HS Code ] 29349990

Hazard Information	Back Directory
[Description] N⁶-Cyclohexyladenosine is an adenosine receptor agonist. It selectively binds to adenosine A₁ receptors in rat cortical membranes (IC₅₀ = 2.3 nM) over A₂ receptors in rat striatal membranes (IC₅₀ = 870 nM). N⁶-Cyclohexyladenosine decreases heart rate and increases coronary flow in a perfused working rat heart model ex vivo (EC₂₅s = 5 and 860 nM, respectively). In vivo, it decreases heart rate and blood pressure in normotensive rats (EC₂₅s = 2.4 and 4.2 μg/kg, respectively). N⁶-Cyclohexyladenosine (100 μM) induces sleep in rats when administered via basal forebrain infusion. N⁶-Cyclohexyladenosine also decreases locomotor activity in mice (ED₅₀ = 60 μg/kg, i.p.).
[Uses] N6-Cyclohexyladenosine is a derivative of Adenosine (A280400), and is used testing adenosine A1 and A2A receptor activation for pharmaceuticals such as antidepressants. N6-Cyclohexyladenosine also is used as a JAK2 inhibitor, blocking STAT3 signalling in human cancer cells.
[Biochem/physiol Actions] Selective A1 adenosine receptor agonist.
[storage] Store at -20°C

Spectrum Detail	Back Directory
[Spectrum Detail] N6-CYCLOHEXYLADENOSINE(36396-99-3)¹HNMR

36396-99-3 suppliers list

Company Name:	ATK CHEMICAL COMPANY LIMITED
Tel:	+undefined-21-51877795
Website:	www.atkchemical.com

Company Name:	Nanjing Baifuli Technology Co., Ltd.
Tel:	+86-15335185688
Website:	www.chemicalbook.com/ShowSupplierProductsList1787360/0.htm

Company Name:	Amadis Chemical Company Limited
Tel:	571-89925085
Website:	http://www.amadischem.com

Company Name:	Nanjing Chemlin Chemical Co., Ltd
Tel:	025-83697070
Website:	www.echemlin.cn

Company Name:	Hangzhou Sage Chemical Co., Ltd.
Tel:	+86057186818502 13588463833
Website:	www.sagechem.com

Company Name:	Chengdu NoVi Biotechnology Co., Ltd.
Tel:	028-81458053
Website:	www.chemicalbook.com/ShowSupplierProductsList15717/0.htm

Company Name:	Nanjing Baifuli Technology Co., Ltd.
Tel:	25-25-58740604 15951658055
Website:	http://www.unisyn.cn/

Company Name:	Zhengzhou Alfachem Co., Ltd.
Tel:	0371-53765687 18937137882
Website:	https://www.chemicalbook.com/supplier/10084342/

Company Name:	ATK CHEMICAL COMPANY LIMITED
Tel:	021-51619050 13301662590
Website:	www.atkchemical.com

Tags:36396-99-3 Related Product Information

137-26-8

HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.

Login