| Identification | Back Directory | [Name]
bucumolol hydrochloride | [CAS]
36556-75-9 | [Synonyms]
CS 359
Bucumarol
Bucumalol
Bucumarol (HCl)
bucumolol hydrochloride
dl-Bucumolol hydrochloride
8-(2-Hydroxy-3-tert-butylaminopropoxy)-5-methylcoumarin hydrochloride
DL-5-Methyl-8-(2-hydroxy-3-tert-butylaminopropoxy)coumarin hydrochloride
(+-)-5-Methyl-8-(2-hydroxy-3-tert-butylaminopropoxy)coumarin hydrochloride | [Molecular Formula]
C17H23NO4.ClH | [MDL Number]
MFCD01662697 | [MOL File]
36556-75-9.mol | [Molecular Weight]
341.833 |
| Hazard Information | Back Directory | [Originator]
Bucumarol,Sankyo,Japan,1982 | [Definition]
ChEBI: Bucumolol hydrochloride is a member of coumarins. | [Manufacturing Process]
A mixture of 3 g of 8-(2-hydroxy-3-chloropropoxy)-5-methyl coumarin, 4.3 g
of t-butylamine and 60 ml of ethanol is heated at 100°C in a sealed tube for
15 hours. The reaction mixture is concentrated under reduced pressure to
dryness. The residue is recrystallized from a mixture of ethanol and ether to
give 2.1 g of the desired product melting at 226° to 228°C (with
decomposition).
In practice it is usually used as hydrochloride. | [Therapeutic Function]
Beta-adrenergic blocker |
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