| Identification | Back Directory | [Name]
9-OXO-15S-HYDROXY-PROSTA-5Z,8(12),13E,17Z-TETRAEN-1-OIC ACID | [CAS]
36614-32-1 | [Synonyms]
PGB3
PROSTAGLANDIN B3
DQRGQQAJYRBDRP-UNBCGXALSA-N
9-OXO-15S-HYDROXY-PROSTA-5Z,8(12),13E,17Z-TETRAEN-1-OIC ACID
(5Z,13E,15S,17Z)-15-Hydroxy-9-oxoprosta-5,8(12),13,17-tetraen-1-oic acid
7-[2-[(3S)-3-hydroxyocta-1,5-dienyl]-5-oxocyclopenten-1-yl]hept-5-enoic acid | [Molecular Formula]
C20H28O4 | [MDL Number]
MFCD00797637 | [MOL File]
36614-32-1.mol | [Molecular Weight]
332.43 |
| Chemical Properties | Back Directory | [solubility ]
DMF: >75 mg/ml (from PGB2); DMSO: >50 mg/ml (from PGB2); Ethanol: >100 mg/ml (from PGB2); PBS pH 7.2: >2 mg/ml (from PGB2) |
| Hazard Information | Back Directory | [Description]
Prostaglandin B3 (PGB3) is a non-enzymatic dehydration product resulting from the treatment of Prostaglandin E3 (PGE3) with strong base. In a structure-activity binding study to determine the affinity of various prostaglandins to human PPARγ, PGB3 exhibited a Ki value greater than 1 mM. In contrast, PGB1 and PGB2 showed significantly higher affinity for PPARγ, with Ki values of 26 and 77 μM, respectively, the same assay. |
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