Identification | Back Directory | [Name]
MST-312 | [CAS]
368449-04-1 | [Synonyms]
MST-312 MST-312 >=98% (HPLC) TELOMERASE INHIBITOR IX N,N′-1,3-Phenylenebis-[2,3-dihydroxy-benzamide] Benzamide, N,N'-1,3-phenylenebis[2,3-dihydroxy- N,N'-BIS(2,3-DIHYDROXYBENZOYL)-1,3-PHENYLENEDIAMINE Telomerase Inhibitor IX - CAS 368449-04-1 - Calbiochem N-[3-[(2,3-dihydroxybenzoyl)amino]phenyl]-2,3-dihydroxybenzamide EGCG,Telomerase,epigallocatechin,gallate,Inhibitor,multiple,tea,MST-312,derivative,cancer,MST 312,inhibit,MST312,myeloma | [Molecular Formula]
C20H16N2O6 | [MDL Number]
MFCD06411458 | [MOL File]
368449-04-1.mol | [Molecular Weight]
380.35 |
Hazard Information | Back Directory | [Uses]
MST-312 has been used in cell invasion assay using mouse fibroblast cells (NIH-3T3) and in the co-immunoprecipitation experiments in colon fibroblast. | [Definition]
ChEBI: N-[3-[[(2,3-dihydroxyphenyl)-oxomethyl]amino]phenyl]-2,3-dihydroxybenzamide is a member of benzamides. | [General Description]
A cell-permeable, bis-catechol containing, m-phenylenediamide compound that displays anti-proliferative properties. Acts as a potent, reversible inhibitor of telomerase activity (IC50 = 670 nM, TRAP lysate prepared from U937 cells). Prolonged treatment with MST-312 has been reported to result in telomere shortening and growth arrest in U937 cells. Does not inhibit the activity of Taq DNA polymerase (IC50 >3 μM). | [Biochem/physiol Actions]
Cell permeable: yes | [storage]
Store at -20°C |
|
Company Name: |
Sigma-Aldrich
|
Tel: |
021-61415566 800-8193336 |
Website: |
https://www.sigmaaldrich.cn |
Company Name: |
BOC Sciences
|
Tel: |
|
Website: |
https://www.bocsci.com |
Company Name: |
DC Chemicals
|
Tel: |
021-58447131 13564518121 |
Website: |
https://www.chemicalbook.com/ShowSupplierProductsList927327/0.htm |
Company Name: |
Energy Chemical
|
Tel: |
021-58432009 400-005-6266 |
Website: |
http://www.energy-chemical.com |
|