| Identification | Back Directory | [Name]
ara-ATP | [CAS]
3714-60-1 | [Synonyms]
ara-ATP
Arabino-ATP
ara-Adenosine-5'-triphosphate
ara-Adenosine-5'-triphosphate (ara-ATP)
9-β-D-Arabinofuranosyl adenine 5′-triphosphate
Ara-adenosine-5'-triphosphate (ara-ATP) (aqueous solution)
Ara-adenosine-5'-triphosphate (ara-ATP) (aqueous solution)
Adenine 9-β-D-arabinofuranoside 5′-triphosphate sodium salt
1-(6-Amino-9H-purin-9-yl)-1-deoxy-β-D-arabinofuranose 5-triphosphoric acid
9-[5-O-[[(Phosphonooxy)phosphonyloxy]phosphonyl]-β-D-arabinofuranosyl]-9H-purine-6-amine
9H-Purin-6-amine, 9-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-arabinofuranosyl]- | [Molecular Formula]
C10H16N5O13P3 | [MDL Number]
MFCD30749216 | [MOL File]
3714-60-1.mol | [Molecular Weight]
507.181 |
| Hazard Information | Back Directory | [Enzyme inhibitor]
This ATP and dATP analogue (FWfree-acid = 507.18 g/mol; CAS 3714-60-1), also known as 9-(5-O-(hydroxy(hydroxy(phosphonooxy) phosphinyl)phosphinyl)-b-D-arabinofuranosyl)-9H-purin-6-amine,Ara-ATP, adenine arabinoside 5’-triphosphate, and vidarabine 5’-triphosphate, is incorporated into viral DNA, thus inhibiting viral polymerase-mediated DNA synthesis via chain termination. Note: Some DNA polymerases are known to extend chains ending in the ara-nucleotide. Ara-ATP is available commercially for in vitro experimentation. Target(s): DNA primase; mRNA translocation; DNA-directed DNA polymerase; DNA polymerase a; DNA polymerase b; DNA polymerase g; ribonucleotide reductase; S-adenosylhomocysteine hydrolase; RNA polymerase; polynucleotide adenylyltransferase; GMP synthetase; lysyltRNA synthetase; leucyl-tRNA synthetase; adenylate cyclase; [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase, possible alternative substrate; duck hepatitis B virus reverse transcriptase; RNA-directed DNA polymerase; DNA nucleotidyl exotransferase, or terminal deoxyribonucleotidyl transferase. |
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BOC Sciences
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16314854226 |
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www.chemicalbook.com/showsupplierproductslist1701258/0.htm |
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