| Identification | Back Directory | [Name]
2,4-DIBENZYL-5-OXOTHIADIAZOLIDINE-3-THIONE | [CAS]
373357-10-9 | [Synonyms]
OTDZT
GSK-3BETA INHIBITOR III
2,4-DIBENZYL-5-OXOTHIADIAZOLIDINE-3-THIONE
2,4-DIBENZYL-3-THIOXO-[1,2,4]THIADIAZOLIDIN-5-ONE
1,2,4-Thiadiazolidine-3,5-dione, 2,4-bis(phenylmethyl)- | [Molecular Formula]
C16H14N2O2S | [MDL Number]
MFCD04973590 | [MOL File]
373357-10-9.mol | [Molecular Weight]
298.36 |
| Chemical Properties | Back Directory | [Melting point ]
104-107°C | [storage temp. ]
-20°C Freezer | [solubility ]
Chloroform, Dichloromethane, Ethyl Acetate | [form ]
Solid | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Uses]
Glycogen Synthase Kinase-3? is a highly conserved ubiquitously expressed serine/threonine protein kinase involved in signal transduction cascades of multiple cellular processes. An oxothiadiazolidine-3-thione analogue that acts as a non-ATP competitive inhibitor of GSK-3? ( IC50 =10uM). |
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