| Identification | Back Directory | [Name]
L-NORPSEUDOEPHEDRINE | [CAS]
37577-07-4 | [Synonyms]
L-NORPSEUDOEPHEDRINE
l-Pseudonorephedrine
(-)-Pseudo Norephedrine
(R,R)-(-)-Norpseudoephedrine
(1R,2R)-(-)-Norpseudoephedrine
(1R,2R)-2-AMino-1-phenyl-1-propanol
(1R,2R)-2-Amino-1-phenylpropane-1-ol
(R)-α-[(R)-1-Aminoethyl]benzenemethanol
(-)-threo-2-AMino-2-Methyl-1-phenylethanol
[R-(R*,R*)]-α-(1-aMinoethyl)benzeneMethanol
Benzenemethanol, α-[(1R)-1-aminoethyl]-, (αR)-
(-) -Pseudonorephedrine, (1R,2R)-2-Amino-1-phenyl-1-propanol, (R,R)-α-(1-Aminoethyl)benzenemethanol, L-(-)-Norpseudoephedrine | [Molecular Formula]
C9H13NO | [MDL Number]
MFCD01711267 | [MOL File]
37577-07-4.mol | [Molecular Weight]
151.21 |
| Hazard Information | Back Directory | [Uses]
An enatiomer of (+)-Pseudonorephedrine (P839585). (-)-Pseudonorephedrine is metabolite of Cathinone (C225700) and possesses amphetamine-like stimulus properties. Studies show that (-)-Pseudonorephedri
ne enhances the analgesic and rate decreasing effects of Morphine (M652290) but inhibits discriminative properties. | [Definition]
ChEBI: Phenylpropanolamine is an amphetamine in which the parent 1-phenylpropan-2-amine skeleton is substituted at position 1 with an hydroxy group. A decongestant and appetite suppressant, it is commonly used in prescription and over-the-counter cough and cold preparations. It has a role as a sympathomimetic agent and a nasal decongestant. | [Purification Methods]
Purify (-)-nor--ephedrine by recrystallisation from H2O, MeOH, EtOH, Et2O/pet ether or *C6H6 (plates). The mandelate salt has m 163.5o (from EtOH/Et2O) and [] D -41.3o (c 0.8, H2O) [Jarowski & Hartung J Org Chem 8 564 566 567 1943]. The hydrochloride is purified by dissolving 1.44g in 96% EtOH (5mL), adding Et2O (16mL) and cooling; it has m 178-179o (m180-181o is also reported) and [] 30D -42.9o (c 1.8, H2O) [Fles & Markovac-Prpic Croat Chem Acta 29 186 1957]. [Beilstein 13 I 252, 13 II 370, 13 III 1716, 13 IV 1874.] |
|