ChemicalBook--->CAS DataBase List--->37836-90-1

37836-90-1

37836-90-1 Structure

37836-90-1 Structure
IdentificationBack Directory
[Name]

2-(7-methoxy-4-methylquinazolin-2-yl)guanidine
[CAS]

37836-90-1
[Synonyms]

MPO inhibitor 28
Myeloperoxidase inhibitor 28
2-(7-methoxy-4-methylquinazolin-2-yl)guanidine
Guanidine, N-(7-methoxy-4-methyl-2-quinazolinyl)-
[Molecular Formula]

C11H13N5O
[MOL File]

37836-90-1.mol
[Molecular Weight]

231.25
Chemical PropertiesBack Directory
[Boiling point ]

442.7±37.0 °C(Predicted)
[density ]

1.40±0.1 g/cm3(Predicted)
[storage temp. ]

Keep in dark place,Sealed in dry,2-8°C
[solubility ]

DMSO:34.37(Max Conc. mg/mL);148.6(Max Conc. mM)
[form ]

A solid
[pka]

7.83±0.30(Predicted)
[color ]

Off-white to light yellow
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Biological Activity]

Compound 18 is an agonist of Aedes aegypti mosquitoes NPY-like receptor 7 (NPYLR7) th at inhibit mosquito attraction to humans and other hosts. Compound 18 suppresses biting and blood-feeding on a live host. AlsoIt (MPO-IN-28) is a potent myeloperoxidase (MPO) inhibitor with an IC50 of 44 nM.
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