| Identification | Back Directory | [Name]
Butanilicaine hydrochloride | [CAS]
3785-21-5 | [Synonyms]
butanilicaine
Butanilicaina
Butacetoluide
Butanilicainum
3003 BUTANILICAINE
Butanilicainum [inn-latin]
2081-65-4 (Phosphate[1:1])
Butanilicaina [inn-spanish]
BUTANILICAINE HYDROCHLORIDE
6027-28-7 (Mono-hydrochloride)
2-butylamino-6-chloroacet-o-toluidide
2-Butylamino-6'-chloro-o-acetotoluidide
2-Butylamino-N-(2-chloro-6-methylphenyl)acetamide
2-(Butylamino)-N-(2-methyl-6-chlorophenyl)acetamide
Acetamide, 2-(butylamino)-N-(2-chloro-6-methylphenyl)-
2-(Butylamino)-N-(2-chloro-6-methylphenyl)acetamide hydrochloride | [Molecular Formula]
C13H19ClN2O | [MDL Number]
MFCD00864434 | [MOL File]
3785-21-5.mol | [Molecular Weight]
254.76 |
| Chemical Properties | Back Directory | [Melting point ]
45-46° | [Boiling point ]
bp0.001 145°; bp0.5 166-167° | [density ]
1.129±0.06 g/cm3(Predicted) | [storage temp. ]
Refrigerator | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
13.41±0.70(Predicted) | [color ]
Pale Brown to Light Brown | [NIST Chemistry Reference]
Butanilicaine(3785-21-5) |
| Hazard Information | Back Directory | [Originator]
Butanilicaine,Enreco, INC | [Uses]
Butanilicaine Hydrochloride, is a local anesthetic. | [Definition]
ChEBI: An amino acid amide amide in which N-butylglycine and 2-chloro-6-methylaniline have combined to form the amide bond; used as a local anaesthetic (amide caine). | [Manufacturing Process]
To a solution of 4-bromo-2-methylaniline is added 13 g of chloroacetyl
chloride. After the reaction is finished to the mixture id added a solution of 33
g sodium acetate in 138 ml of water. Chloroacetic acid 4-bromo-2-
methylanilide is filtered; yield 24 g, M.P. 135°C (crystallization from ethanol).
20 g of chloroacetic acid 4-bromo-2-methylanilide is dissolved in 200 ml of butylamine. After about 15 hours to the solution is added 2 N hydrochloric
acid. Butylaminoacetic acid 4-bromo-2-methylanilide hydrochloride is removed
by suction and washed with water; yield 90%, M.P. 252-253°C (from
methanol). | [Therapeutic Function]
Local anesthetic |
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