| Identification | Back Directory | [Name]
16-PHENYL TETRANOR PROSTAGLANDIN E2 | [CAS]
38315-44-5 | [Synonyms]
DXWJXQSQVUJRNS-YYWARMNLSA-N
16-PHENYL TETRANOR PROSTAGLANDIN E2
9-OXO-11ALPHA-15S-DIHYDROXY-16-PHENYL-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID | [Molecular Formula]
C22H28O5 | [MDL Number]
MFCD00797648 | [MOL File]
38315-44-5.mol | [Molecular Weight]
372.45 |
| Chemical Properties | Back Directory | [solubility ]
DMF: >100 mg/ml (from Fluprostenol); DMSO: >100 mg/ml (from Fluprostenol); Ethanol: >100 mg/ml (from Fluprostenol); PBS pH 7.2: >0.8 mg/ml |
| Hazard Information | Back Directory | [Description]
16-phenyl tetranor PGE2 is a metabolically stable synthetic analog of PGE2. 16-phenyl tetranor PGE2 is five times more potent than PGE2 in causing hypotension in dogs (0.1 μg/kg dose).1 It is comparable to PGE2 in inhibiting histamine-induced bronchoconstriction in conscious guinea pigs.1 | [Definition]
ChEBI: 16-Phenyl-tetranor-PGE2 is a prostanoid. | [References]
1. Johnson, M.R., Schaaf, T.K., Constantine, J.W., et al. Structure activity studies leading to a tissue-selective hypotensive prostaglandin analog, 13,14-dihydro-16-phenyl-ω-tetranor PGE2 Prostaglandins 20(3),515-520(1980). |
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