ChemicalBook--->CAS DataBase List--->39544-74-6

39544-74-6

39544-74-6 Structure

39544-74-6 Structure
IdentificationBack Directory
[Name]

BENZOTRIPT
[CAS]

39544-74-6
[Synonyms]

benzotripte
BENZOTRIPT USP/EP/BP
Nα-(4-Chlorobenzoyl)-L-tryptophan
L-Tryptophan, N-(4-chlorobenzoyl)-
(S)-α-(4-Chlorobenzoylamino)-1H-indole-3-propionic acid
[EINECS(EC#)]

254-500-0
[Molecular Formula]

C18H15ClN2O3
[MOL File]

39544-74-6.mol
[Molecular Weight]

342.78
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[solubility ]

Soluble in DMSO (up to at least 25 mg/ml)
[form ]

solid
[color ]

White
[Stability:]

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Hazard InformationBack Directory
[Description]

Benzotript (39544-74-6) antagonizes the interaction of cholecystokinin and related peptides with the cholecystokinin receptor.1 ?It has been reported to potentiate morphine analgesia via interaction with opioid receptors.2
[Uses]

Benzotript is an antiulcer drug that is a cholecystokinin receptor (CCK-2R) antagonist .
[References]

1) Hahne (1981), Proglumide and benzotript: Members of a different class of cholecystokinin receptor antagonists; Proc. Natl. Acad. Sci. USA. 78 6304 2) Gaudreau et al. (1990), Cholecystokinin antagonists proglumide, lorglumide and benzotript, but not L-364,718, interact with brain opioid binding sites; Neuropeptides 16 51
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