| Identification | Back Directory | [Name]
10,11-DIBROMO-10,11-DIHYDRO-5H-DIBENZO[A,D]CYCLOHEPTEN-5-ONE | [CAS]
39654-52-9 | [Synonyms]
Cyclobenzaprine Impurity 2
TRANS-10,11-DIBROMODIBENZOSUBERONE
10,11-Dibromo10,11-dihydro-5-dibenzosuberenone
10,11-DIBROMO-10,11-DIHYDRO-5H-DIBENZO[A,D]CYCLOHEPTEN-5-ONE
5H-Dibenzo[a,d]cyclohepten-5-one,10,11-dibromo-10,11-dihydro-, (10R,11R)-rel- | [Molecular Formula]
C15H10Br2O | [MDL Number]
MFCD20486792 | [MOL File]
39654-52-9.mol | [Molecular Weight]
366.05 |
| Hazard Information | Back Directory | [Uses]
10,11-Dibromo10,11-dihydro-5-dibenzosuberenone is an intermediate in the synthesis of 10-Hydroxy (E)-Amitriptyline (D462790). (5E)-5-[3-(dimethylamino)propylidene]-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-10-ol is a metabolite of amitriptyline (A633350) which is a dibenzocycloheptadiene derivative and an antidepressant (1). Amitriptyline is also a TrkA and TrkB receptor agonist and exhibits neurotrophic and anti-inflammatory activities (2,3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). |
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