| Identification | Back Directory | [Name]
Doxorubicin-SMCC | [CAS]
400647-59-8 | [Synonyms]
Doxorubicin-SMCC
N-(4-((2,5-dioxo-2H-pyrrol-1(5H)-yl)methyl)cyclohexane)-Doxorubicin
5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-[[[4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]cyclohexyl]carbonyl]amino]-α-L-lyxo-hexopyranosyl]oxy]-, (8S,10S)- | [Molecular Formula]
C39H42N2O14 | [MDL Number]
MFCD32004617 | [MOL File]
400647-59-8.mol | [Molecular Weight]
762.76 |
| Questions And Answer | Back Directory | [Uses]
Doxorubicin-SMCC is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). | [In vitro]
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. MCE has not independently confirmed the accuracy of these methods. They are for reference only. | [Storage]
Please store the product under the recommended conditions in the Certificate of Analysis. |
| Chemical Properties | Back Directory | [Melting point ]
162-172 °C | [Boiling point ]
1022.5±65.0 °C(Predicted) | [density ]
1.56±0.1 g/cm3(Predicted) | [solubility ]
Soluble in DMSO, DMF | [form ]
Solid | [pka]
7.35±0.60(Predicted) | [color ]
Orange to red |
| Hazard Information | Back Directory | [Description]
N-(4-((2,5-dioxo-2H-pyrrol-1(5H)-yl)methyl)cyclohexane)-Doxorubicin is a maleimide attached Doxorubicin. It can conjugate with thiol containing molecules. |
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| Company Name: |
Abydos Scientific
|
| Tel: |
025-84767922 18936879710 |
| Website: |
http://www.abydoscientific.com/index.html |
| Company Name: |
InvivoChem
|
| Tel: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
|