Identification | Back Directory | [Name]
5BETA,6BETA-EPOXYCHOLESTAN-3BETA-OL | [CAS]
4025-59-6 | [Synonyms]
BETA-EPOXYCHOLESTEROL cholesterolbeta-epoxide 5-BETA-EPOXYCHOLESTEROL 5β,6β-epoxy Cholestanol cholesterol-5B,6B-epoxide CHOLESTERYL -BETA-EPOXIDE Cholestan-5β,6β-epoxy-3β-ol CHOLESTEROL-5BETA,6BETA-EPOXIDE 5 beta, 6 beta-Epoxy-Cholestanol 5BETA,6BETA-EPOXYCHOLESTAN-3BETA-OL 5,6beta-epoxy-5beta-cholestan-3beta-ol Cholestan-3-ol, 5,6-epoxy-, (3b,5b,6b)- Cholestan-3-ol, 5,6-epoxy-, (3β,5β,6β)- CHOLESTAN-5-BETA, 6-BETA-EPOXY-3-BETA-OL 5,6-beta-epoxy-5-beta-cholestan-3-beta-o (3beta,5beta,6beta)-5,6-epoxy-Cholestan-3-ol 5,6-epoxy-,(3-beta,5-beta,6-beta)-cholestan-3-o | [Molecular Formula]
C27H46O2 | [MDL Number]
MFCD00201258 | [MOL File]
4025-59-6.mol | [Molecular Weight]
402.65 |
Chemical Properties | Back Directory | [storage temp. ]
room temp | [solubility ]
DMF: 2 mg/ml; DMSO: 0.1 mg/ml; Ethanol: 20 mg/ml; Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml | [form ]
A crystalline solid | [color ]
White to off-white |
Hazard Information | Back Directory | [Uses]
Cholesterol 5beta,6beta-epoxide is an oxysterol produced as an oxidation product of cholesterol. | [Definition]
ChEBI: Cholesterol beta-epoxide is 5,6beta-epoxy-5beta-cholestan-3beta-ol It is a 3beta-hydroxy steroid, an oxysterol and an epoxy steroid. It derives from a hydride of a 5beta-cholestane. | [Biological Activity]
Cholesterol 5β,6β-epoxide is an oxysterol produced as an oxidation product of cholesterol. Oxysterols are cytotoxic and induce death in monocytessmooth muscle cells and endothelial cells. The mechanism of apoptosis induced by oxysterols may involve caspases or DNA fragmentation. |
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