| Identification | Back Directory | [Name]
6-tert-butyl-2-(furan-2-carboxaMido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid | [CAS]
407587-33-1 | [Synonyms]
CaCCinh-A01
TMEM16 BLOCKER I
CaCC(inh)-A01, TMEM16 Blocker I.
CACCINH-A01; CACC(INH)-A01, TMEM16 BLOCKER I.
6-tert-butyl-2-(furan-2-carboxaMido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid
6-(1,1-Dimethylethyl)-2-[(2-furanylcarbonyl)amino]-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid
Benzo[b]thiophene-3-carboxylic acid, 6-(1,1-dimethylethyl)-2-[(2-furanylcarbonyl)amino]-4,5,6,7-tetrahydro- | [Molecular Formula]
C18H21NO4S | [MDL Number]
MFCD02919058 | [MOL File]
407587-33-1.mol | [Molecular Weight]
347.43 |
| Chemical Properties | Back Directory | [Boiling point ]
429.7±45.0 °C(Predicted) | [density ]
1.305±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: soluble20mg/mL, clear | [form ]
powder | [pka]
4.49±0.40(Predicted) | [color ]
white to beige |
| Hazard Information | Back Directory | [Uses]
CaCC(inh)-A01 is a potent, selective class A inhibitor of calcium-activated chloride channels (CaCCs). | [Biochem/physiol Actions]
CaCCinh-A01 is a TMEM16A (transmembrane member 16A) inhibitor. It also blocks anoctamin-1 (ANO1) and decreases cell viability and represses cell migration. | [storage]
Store at -20°C |
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