| Identification | Back Directory | [Name]
GW 766994 | [CAS]
408303-43-5 | [Synonyms]
GW 994
GW 766994
Benzamide, 4-[[[[[[(2S)-4-[(3,4-dichlorophenyl)methyl]-2-morpholinyl]methyl]amino]carbonyl]amino]methyl]- | [Molecular Formula]
C21H24Cl2N4O3 | [MDL Number]
MFCD31656783 | [MOL File]
408303-43-5.mol | [Molecular Weight]
451.35 |
| Chemical Properties | Back Directory | [Boiling point ]
685.8±55.0 °C(Predicted) | [density ]
1.331±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO:56.0(Max Conc. mg/mL);124.07(Max Conc. mM) | [form ]
A solid | [pka]
13.40±0.46(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Description]
GW 766994 is an antagonist of chemokine (C-C motif) receptor 3 (CCR3) with a Ki value of 13.8 nM in an assay of eosinophil chemotaxis induced by chemokine (C-C motif) ligand 11 (CCL11). It decreases CCL11-induced cyclin-dependent kinase 5 (Cdk5) and tau phosphorylation and production of amyloid β (1-42) (Aβ42) in isolated mouse hippocampal neurons when used at a concentration of 10 μM. | [storage]
Store at -20°C |
|
| Company Name: |
cjbscvictory
|
| Tel: |
13348960310 13348960310 |
| Website: |
http://www.weikeqi-biotech.com/ |
| Company Name: |
MedChemExpress
|
| Tel: |
021-58955995 |
| Website: |
www.medchemexpress.com |
|