ChemicalBook--->CAS DataBase List--->4171-13-5

4171-13-5

4171-13-5 Structure

4171-13-5 Structure
IdentificationBack Directory
[Name]

valnoctamide
[CAS]

4171-13-5
[Synonyms]

Axiquel
Nirvani
Nirvanil
NSC-32363
McN-X-181
valnoctamide
Valmethamide
2-Ethyl-3-methylvaleramide
2-Ethyl-3-methylpentan-amide
[EINECS(EC#)]

224-033-7
[Molecular Formula]

C8H17NO
[MDL Number]

MFCD00868184
[MOL File]

4171-13-5.mol
[Molecular Weight]

143.23
Chemical PropertiesBack Directory
[Appearance]

Crystalline Solid
[Melting point ]

113.5-1140C
[Boiling point ]

261.35°C (rough estimate)
[density ]

0.9636 (rough estimate)
[refractive index ]

1.4614 (estimate)
[storage temp. ]

Refrigerator
[solubility ]

DMSO: soluble20mg/mL, clear
[form ]

powder
[pka]

16.81±0.50(Predicted)
[color ]

white to off-white
[Water Solubility ]

8.70g/L(temperature not stated)
Hazard InformationBack Directory
[Chemical Properties]

Crystalline Solid
[Uses]

Isomer of Valpromide. Anxiolytic
[Description]

Valnoctamide is an isomer of the valproic acid amide, valpromide. It has been marketed as an anxiolytic and sedative compound and suppresses neuropathic pain. Unlike valpromide, valnoctamide is not metabolized to its acid form, valnoctic acid, in vivo and has no teratogenicity. It abolishes the activity of myo-inositol-1-phosphate synthase in human brain crude homogenates (Ki = 0.18 mM). Valnoctamide suppresses electrographic seizures in animal models of status epilepticus, suggesting potential applications in managing epilepsy.
[Definition]

ChEBI: Valnoctamide is a fatty amide.
[Brand name]

Axiquel (Ortho-McNeil).
Safety DataBack Directory
[Hazard Codes ]

Xn
[Risk Statements ]

22
[WGK Germany ]

3
[RTECS ]

YV5950000
[Toxicity]

LD50 oral in rat: 760mg/kg
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