| Identification | Back Directory | [Name]
2,3,5,8-Tetrahydroxy-6-methyl-1,4-naphthalenedione | [CAS]
41768-12-1 | [Synonyms]
Methylspinazarin
Methylspinazaline
2,3,5,8-Tetrahydroxy-6-methyl-1,4-naphthalenedione | [MDL Number]
MFCD01327648 | [MOL File]
41768-12-1.mol |
| Hazard Information | Back Directory | [Description]
Methylspinazarin is a naphthoquinone bacterial metabolite that has been found in Streptomyces and is an inhibitor of catechol O-methyltransferase (COMT; IC50 = 0.8 μg/ml). It is selective for COMT over tyrosine hydroxylase, DOPA decarboxylase, and dopamine-β-hydroxylase at 100 μg/ml. Methylspinazarin decreases blood pressure in spontaneously hypertensive rats when administered at a dose of 50 mg/kg. |
|
| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
|