ChemicalBook--->CAS DataBase List--->433212-75-0

433212-75-0

433212-75-0 Structure

433212-75-0 Structure
IdentificationBack Directory
[Name]

Hydrazinecarbothioamide, 2-[1-(2-thienyl)ethylidene]-, (2Z)-
[CAS]

433212-75-0
[Synonyms]

SSAA09E1
SSAA09E1 [(Z)-1-Thiophen-2-ylethylideneamino]thiourea
Hydrazinecarbothioamide, 2-[1-(2-thienyl)ethylidene]-, (2Z)-
[Molecular Formula]

C7H9N3S2
[MOL File]

433212-75-0.mol
[Molecular Weight]

199.3
Chemical PropertiesBack Directory
[Boiling point ]

333.0±34.0 °C(Predicted)
[density ]

1.37±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Ethanol: soluble
[form ]

A crystalline solid
[pka]

11.50±0.70(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Biological Activity]

SSAA09E1 is an inhibitor of severe acute respiratory syndrome coronavirus (SARS-CoV) viral entry.1 It reduces infection of HEK293T cells transiently transfected with angiotensin-converting enzyme 2 (ACE2) by an HIV-based virus system pseudotyped with SARS-CoV surface glycoprotein (EC50 = 6.7 μM). SSAA09E1 also inhibits the proteolytic activity of cathepsin L (IC50 = 5.33 μM) but not cathepsin B when used at a concentration of 20 μM.
[References]

1.()
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