| Identification | Back Directory | [Name]
(R)-AM1241 | [CAS]
444912-51-0 | [Synonyms]
(R)-AM1241
(R)-AM1241 Exclusive
ZUHIXXCLLBMBDW-MRXNPFEDSA-N
(R) AM1241,(R)-AM-1241,(R)AM1241 | [Molecular Formula]
C22H22IN3O3 | [MDL Number]
MFCD06798331 | [MOL File]
444912-51-0.mol | [Molecular Weight]
503.33 |
| Hazard Information | Back Directory | [Description]
(R)-AM1241 binds to cannabinoid (CB) receptors and has greater than 100-fold selectivity for the CB2 over the CB1 receptor (Kis = 15 and 5,000 nM, respectively, in a membrane assay using human receptors). (R)-AM1241 acts as an agonist at human CB2 receptors (EC50 = 118 nM) but an inverse agonist at rat and mouse CB2 receptors (EC50s = 315 and 341 nM, respectively). Similar to the racemate AM1241 , (R)-AM1241 produces antinociception to thermal, but not mechanical, pain in rats. The pain-reducing effect of (R)-AM1241 is blocked by the CB2-specific inhibitor SR 144528 but not by either the CB1-selective inhibitor rimonabant or the opioid receptor blocker naloxone ( | ISO60191). | [Uses]
(R)-AM1241 binds to cannabinoid (CB) receptors and has greater than 100-fold selectivity for the CB2 over the CB1 receptor. Synthetic cannabinoid.Synthetic Cannabinoids | [storage]
Store at -20°C |
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Boao Pike
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010-57798038 15652371397 |
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www.biopike.cn |
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