| Identification | Back Directory | [Name]
3-bromo-N'-[1-(2,4-dihydroxyphenyl)ethylidene]-4-methylbenzohydrazide | [CAS]
468747-17-3 | [Synonyms]
mTOR inhibitor-1
3-bromo-N'-[1-(2,4-dihydroxyphenyl)ethylidene]-4-methylbenzohydrazide
(E)-3-Bromo-N'-[1-(2,4-dihydroxyphenyl)ethylidene]-4-methylbenzohydrazide
3-Bromo-4-methylbenzoic Acid 2-[1-(2,4-Dihydroxyphenyl)ethylidene]hydrazide
Benzoic acid, 3-bromo-4-methyl-, 2-[1-(2,4-dihydroxyphenyl)ethylidene]hydrazide | [Molecular Formula]
C16H15BrN2O3 | [MDL Number]
MFCD03542241 | [MOL File]
468747-17-3.mol | [Molecular Weight]
363.21 |
| Chemical Properties | Back Directory | [density ]
1.48±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 83.33 mg/mL (229.43 mM; Need ultrasonic) | [form ]
Solid | [pka]
7.96±0.40(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
mTOR inhibitor-1 (Compound C-4) is an ATP-Competitive mTOR inhibitor which can suppress cells proliferation and inducing autophagy[1]. | [storage]
Store at -20°C | [References]
[1] Liu J, et al. In Silico Discovery of a Small Molecule Suppressing Lung Carcinoma A549 Cells Proliferation and Inducing Autophagy via mTOR Pathway Inhibition. Mol Pharm. 2018 Nov 5;15(11):5427-5436. DOI:10.1021/acs.molpharmaceut.8b00996 |
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