| Identification | Back Directory | [Name]
Fosinopril impurity C | [CAS]
474519-28-3 | [Synonyms]
Fosinopril impurity C
(2S,4S)-4-Cyclohexyl-1-[[(RS)-[(1RS)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphoryl]acetyl]pyrrolidine-2-carboxylic acid | [Molecular Formula]
C30H46NO7P | [MOL File]
474519-28-3.mol | [Molecular Weight]
563.66 |
| Hazard Information | Back Directory | [Definition]
ChEBI: Fosinopril is a phosphinate ester-containing N-acyl derivative of (4S)-cyclohexyl-L-proline. It is used for the treatment of hypertension and heart failure. A pro-drug, it is hydrolysed in vivo to the corresponding phosphininc acid, fosinoprilat, which is the active metabolite. It has a role as an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor, a prodrug and an antihypertensive agent. It is a phosphinic ester and a L-proline derivative. It is functionally related to a fosinoprilat. It is a conjugate acid of a fosinopril(1-). |
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