| Identification | Back Directory | [Name]
N-[12-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]DODECANOYL]-SPHINGANINE | [CAS]
474943-05-0 | [Synonyms]
NBD-C12-SAFINGOL
C12 NBD SAFINGOL
C12 NBD SPHINGANINE
N-ACYL-SPHINGANINE (C12 NBD)
N-(NBD-AMINOLAUROYL)SAFINGOL
N-(NBD-AMINOLAUROYL)SPHINGANINE
C12 NBD dihydro Ceramide (d18:0/12:0)
N-[12-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]DODECANOYL]-SPHINGANINE
N-[6-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]DODECANOYL]-L-THREO-SPHINGANINE
N-[12-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]DODECANOYL]-L-THREO-SPHINGANINE
N-Dodecanoyl-NBD-D-erythro-dihydrosphingosine, Fluorescent C12:0-dihydrosphingosine analog
N-[12-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]DODECANOYL]-SPHINGANINE;C12-NBD SPHINGANINE
C12-NBD Sphinganine, N-[12-[(7-Nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-sphinganine
NBD-C12-Safingol, N-[6-[(7-Nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-L-threo-sphinganine
Dodecanamide, N-[(1S,2R)-2-hydroxy-1-(hydroxymethyl)heptadecyl]-12-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]- | [Molecular Formula]
C36H63N5O6 | [MDL Number]
MFCD02259241 | [MOL File]
474943-05-0.mol | [Molecular Weight]
661.92 |
| Chemical Properties | Back Directory | [density ]
1.095±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C | [solubility ]
DMF: 30 mg/ml; DMSO: 20 mg/ml; Ethanol: 20 mg/ml | [form ]
A solid | [pka]
14.30±0.20(Predicted) |
| Hazard Information | Back Directory | [Uses]
C-12 NBD-dihydro-Ceramide is a fluorescent ceramidase substrate. C-12 NBD-dihydro-Ceramide compound is a fluorescent ceramide analog which contains a saturated bond in the C4-C5 position of the sphingosine backbone. It can be used for the measurement of alkaline and neutral ceramidase activity from a variety of sources. C-12 NBD-dihydro-ceramide may exhibit reduced activity in ceramidase assays compared to C-12 NBD ceramide. This is based on the observation that saturation of the C4-C5 sphingosine bond in C16-ceramide results in approximately a 10-fold reduction in efficiency as a substrate for rat brain ceramidase compared to the unsaturated substrate. Yet, experimental characterization of C-12 NBD-dihydro-ceramide as a ceramidase substrate needs to be performed. |
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Alfa Chemistry
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Energy Chemical
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