Identification | Back Directory | [Name]
COLCHICOSIDE | [CAS]
477-29-2 | [Synonyms]
Nsc32992 Nsc624672 Aids012001 Aids-012001 COLCHICOSIDE IMPURITY Colchicine impurity D COLCHICOSIDE USP/EP/BP Thiocolchicoside Impurity D Thiocolchicoside EP Impurity D 3-Demethylcolchicine glucoside N-[(7S,12aRa)-3-(beta-D-Glucopyrano Colchicine EP impurity D (Colchicoside) Colchicine Impurity 4(Colchicine EP Impurity D) N-[3-(Hexopyranosyloxy)-1,2,10-trimethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[A]heptalen-7-yl]acetamide (S)-7-Acetylamino-6,7-dihydro-3-(β-D-glucopyranosyloxy)-1,2,10-trimethoxybenzo[a]heptalen-9(5H)-one (S)-N-[3-(β-D-Glucopyranosyloxy)-5,6,7,9-tetrahydro-1,2,10-triMethoxy-9-oxobenzo[a]heptalen-7-yl]acetaMide N-[(7S)-3-(β-D-Glucopyranosyloxy)-5,6,7,9-tetrahydro-
1,2,10-triMethoxy-9-oxobenzo[a]heptalen-7-yl]acetaMide Acetamide, N-[(7S)-3-(β-D-glucopyranosyloxy)-5,6,7,9-tetrahydro-1,2,10-trimethoxy-9-oxobenzo[a]heptalen-7-yl]- N-[(7S,12aRa)-3-(β-D-glucopyranosyloxy)-1,2,10-trimethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide (colchicoside) N-((S)-1,2,10-trimethoxy-9-oxo-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl)acetamide ColchicosideQ: What is
Colchicoside Q: What is the CAS Number of
Colchicoside Q: What is the storage condition of
Colchicoside Q: What are the applications of
Colchicoside | [EINECS(EC#)]
207-513-0 | [Molecular Formula]
C27H33NO11 | [MDL Number]
MFCD01736974 | [MOL File]
477-29-2.mol | [Molecular Weight]
547.554 |
Chemical Properties | Back Directory | [Melting point ]
194-197°C | [Boiling point ]
620.17°C (rough estimate) | [density ]
1.3430 (rough estimate) | [refractive index ]
1.6400 (estimate) | [storage temp. ]
Refrigerator | [solubility ]
DMF: 30 mg/ml; DMSO: 30 mg/ml; PBS (pH 7.2): 10 mg/ml | [form ]
A crystalline solid | [pka]
12.74±0.70(Predicted) | [color ]
Light yellow to yellow |
Hazard Information | Back Directory | [Chemical Properties]
Pale Yellow Solid | [Uses]
A significantly toxic Colchicine analog with no anti-inflammatory properties. | [Definition]
ChEBI: Colchicoside is a carbotricyclic compound, an alkaloid and a member of acetamides. | [Purification Methods]
Purify colchicoside by chromatography through alumina and eluting with CHCl3, then recrystallising from Me2CO, m 275-280o (after releasing solvent at 180o). It also crystallises from EtOH; see colchicine. The tetraacetate has m 175-177o, [] D 15 -57o (c 1, CHCl3). [Bellet et al. Ann Pharm Fr 10 241 1952, Chem Abstr 47 3323 1953, Beilstein 14 IV 946 for colchicine.] |
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