| Identification | Back Directory | [Name]
GLU-THR-PRO-ASP-CYS-PHE-TRP-ORN-TYR-CYS-VAL | [CAS]
479065-85-5 | [Synonyms]
ORN8, UROTENSIN II, HUMAN
GLU-THR-PRO-ASP-CYS-PHE-TRP-ORN-TYR-CYS-VAL
L-Valine, L-α-glutamyl-L-threonyl-L-prolyl-L-α-aspartyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-ornithyl-L-tyrosyl-L-cysteinyl-, cyclic (5→10)-disulfide (9CI) | [Molecular Formula]
C63H83N13O18S2 | [MDL Number]
MFCD07366697 | [MOL File]
479065-85-5.mol | [Molecular Weight]
1374.54 |
| Chemical Properties | Back Directory | [storage temp. ]
Desiccate at -20°C | [solubility ]
Soluble to 100 mM in DMSO and to 100 mM in ethanol | [form ]
solid | [color ]
White lyophilised |
| Hazard Information | Back Directory | [Description]
Inhibitor of glycogen synthase kinase-3 (GSK-3); derived from
FRAT1, the mammalian version of GSK-3-binding protein. Binds
to GSK-3, inhibiting its interaction with axin, and also blocks
GSK-3-catalyzed phosphorylation of axin and β-catenin. Does
not affect GSK-3-mediated phosphorylation of glycogen
synthase or eIF2B. | [storage]
Desiccate at -20°C |
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