| Identification | Back Directory | [Name]
MMPIP HYDROCHLORIDE | [CAS]
479077-02-6 | [Synonyms]
MMPIP
MMPIP HYDROCHLORIDE
6-(4-Methoxyphenyl)-5-methyl-3-(4-pyridinyl)-isoxazolo[ 4,5-c]pyridin-4(5H)-one
Isoxazolo[4,5-c]pyridin-4(5H)-one, 6-(4-methoxyphenyl)-5-methyl-3-(4-pyridinyl)-
6-(4-METHOXYPHENYL)-5-METHYL-3-(4-PYRIDINYL)-ISOXAZOLO[4,5-C]PYRIDIN-4(5H)-ONE HYDROCHLORIDE | [Molecular Formula]
C19H15N3O3 | [MDL Number]
MFCD12195836 | [MOL File]
479077-02-6.mol | [Molecular Weight]
333.34 |
| Chemical Properties | Back Directory | [Boiling point ]
603.2±55.0 °C(Predicted) | [density ]
1.292±0.06 g/cm3(Predicted) | [storage temp. ]
Desiccate at RT | [solubility ]
DMSO: ≥10mg/mL | [form ]
powder | [pka]
2.15±0.10(Predicted) | [color ]
white to off-white |
| Hazard Information | Back Directory | [Uses]
MMPIP Hydrochloride is a reversible allosteric antagonist of the metabotropic glutamate receptor 7 (mGluR7) that blocks agonist-induced calcium mobilization. | [Biological Activity]
Potent allosteric mGlu 7 -selective receptor antagonist. Inhibits agonist-induced intracellular calcium mobilization and cAMP accumulation (IC 50 values are 26 and 610 nM). Displays intrinsic activity; increases forskolin-induced cAMP accumulation in the absence of an agonist (IC 50 = 15 nM), indicating inverse agonist activity. | [storage]
Store at -20°C |
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Wuhan Topule
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