Identification | Back Directory | [Name]
1-(2-HYDROXYETHYL)-2-HYDROXYMETHYL-5-NITROIMIDAZOLE | [CAS]
4812-40-2 | [Synonyms]
MNZOH METRONIDAZOLE-OH Hydroxy Metronidazo Metronidazole-hydroxy HYDROXY METRONIDAZOLE Metronidazole-OH
MNZOH Metronidazole Impurity H 2-(HydroxyMethyl)-5-nitro- Metronidazole EP Impurity H ROXYMETHYL-5-NITROIMIDAZOLE 1-(2-Hydroxyethyl)-2-hydroxymethyl- Metronidazole-hydroxy solution,100ppm 2-hydroxymethyl-5-nitro-imidazole-1-ethano MNZOH, Hydroxy metronidazole Solution, 100ppm 4-Hydroxy-2-methyl-5-nitro-1H-imidazole-1-ethanol 1H-IMidazole-1-ethanol, 2-(hydroxyMethyl)-5-nitro- 1-(2-HYDROXYETHYL)-2-HYDROXYMETHYL-5-NITROIMIDAZOLE Metronidazole-hydroxy solution,1000ppm solution,100ppm 1-(2-Hydroxyethyl)-2-hydroxymethyl-5-nitroimidazole (Hydroxy 1-(2-Hydroxyethyl)-2-hydroxymethyl-5-nitroimidazole, Hydroxymetronidazole, MNZOH Metronidazole-OH,1-(2-Hydroxyethyl)-2-hydroxymethyl-5-nitroimidazole, Hydroxymetronidazole, MNZOH Hydroxy MetronidazoleQ: What is
Hydroxy Metronidazole Q: What is the CAS Number of
Hydroxy Metronidazole Q: What is the storage condition of
Hydroxy Metronidazole Q: What are the applications of
Hydroxy Metronidazole Hydroxy Metronidazole D2Q: What is
Hydroxy Metronidazole D2 Q: What is the CAS Number of
Hydroxy Metronidazole D2 Q: What is the storage condition of
Hydroxy Metronidazole D2 Q: What are the applications of
Hydroxy Metronidazole D2 | [Molecular Formula]
C6H9N3O4 | [MDL Number]
MFCD01721480 | [MOL File]
4812-40-2.mol | [Molecular Weight]
187.15 |
Chemical Properties | Back Directory | [Melting point ]
118-121°C | [Boiling point ]
321.89°C (rough estimate) | [density ]
1.4796 (rough estimate) | [refractive index ]
1.5800 (estimate) | [storage temp. ]
-20?C Freezer | [solubility ]
DMSO (Sparingly), Methanol (Slightly) | [form ]
neat | [pka]
13.28±0.10(Predicted) | [color ]
White to Light Beige |
Hazard Information | Back Directory | [Description]
Hydroxy metronidazole is a metabolite of metronidazole. Metronidazole belongs to the nitroimidazole class of drugs. In agricultural production, it is often used as a drug to expel parasites in animals. After being added to animal feed, metronidazole remains in eggs. Because metronidazole has a variety of toxic and side effects on the human body, especially its potential carcinogenicity and hereditary mutation effects, and metronidazole can be rapidly distributed throughout the body after entering the human body, so the residual metronidazole and its metabolites in eggs inspection is necessary. | [Chemical Properties]
Off-White Solid | [Uses]
A metabolite of Metronidazole (M338880). | [Definition]
ChEBI: Metronidazole-OH is a member of imidazoles and a C-nitro compound. | [Biological Activity]
Hydroxymetronidazole is an active metabolite of the antibiotic metronidazole (Item No. 9002409). It is formed from metronidazole primarily by the cytochrome P450 (CYP) isoform CYP2A6. Hydroxymetronidazole is active against B. fragilis, B. thetaiotaomicron, B. distasonis, and B. ovatus (MICs = 1, 2, 1, and 2 μg/ml, respectively). It has been found in pork and porcine plasma. |
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